Micro and Nano Plastics – Rodent Health Effects Explored

The abstract of an April 21, 2022 Particle and Fibre Toxicology article https://particleandfibretoxicology.biomedcentral.com/articles/10.1186/s12989-022-00473-y#Sec1 by researchers with the Germany Leibniz Institute for Plasma Science and Technology and others reports that “… The ubiquitous nature of micro- (MP) and nanoplastics (NP) is a growing environmental concern. However, their potential impact on human health remains unknown. Research increasingly focused on using rodent models to understand the effects of exposure to individual plastic polymers. In vivo data showed critical exposure effects depending on particle size, polymer, shape, charge, concentration, and exposure routes. Those effects included local inflammation, oxidative stress, and metabolic disruption, leading to gastrointestinal toxicity, hepatotoxicity, reproduction disorders, and neurotoxic effects. This review distillates the current knowledge regarding rodent models exposed to MP and NP with different experimental designs assessing biodistribution, bioaccumulation, and biological responses …” #PlasticWaste #SingleUsePlastic #MicroPlastics #NanoPlastics @INPGreifswald @BioMedCentral